The Salient network optimizes interactions with the environment (Central Executive Network) and internal representations(the Default Mode Network) Networks units constrain each other via synaptic activity. The constraints are satisfied via transmitting of signals. When the network is strained by perturbations ‘Multiple Constraint Frustration’ occurs with the ‘Emergence Property’ of Anxiety. These alteration involve minutes-range activity.

Massive spread increase of plasticity will ‘absorb’ instability and stabilize the networks eliminating anxious emergence.
NEUROMODULATION
Concentrate on test-retest analysis within minutes time-scales. Expect to find erratic unstable activity spread in the cortex, expressed in connectivity matrix values, and graph analysis values at edges.