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Top-Down Hierarchal Shift as part of an hierarchal imbalance constrains and biases upcoming experience creating false ideation (Delusions) about transpiring Experience. These alteration involve millisecond-range neuronal and cognitive activity.

Positive Signs Delusions

Aim to reduce prefrontal activation using inhibitory modulation. Increase bottom-up connectivity by stimulating unimodal multimodal activity in comparison to trans modal higher-level connectivity  

NEUROMODULATION

Expect reduction in parameters of correlation matrixes and reduced weights on graph analysis edges. Expect reduced degrees for Hubs spread out globally in the brain. Identify disturbance of small-world dynamics toward random unstable measurements  

IMAGING

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