Personality Disorders

Maturation and development of the Default-Mode-Network is a life-long process of interacting with the environmental  experiences. It is an experience –dependent plasticity process. Any disturbance to this process, including unstable environments, hampers Default-Mode-Network maturation. Immature mismatching biased internal  Representations cause non-adaptive faulty psychosocial functionality (personality disorders), deoptimization(mood alterations) and instability (anxiety) and possible fragmentation with psychotic vulnerability                      

IMAGING

Changes are expected in timescales of years. Most notably the network maturation should be measured in terms of small- worldliness  as it is expected that the maturing brain assumes small-world organization as it matures. Alife-trajectory of mature brains should be compared with trajectories of immature personality-disordered brains and a ‘bias measure’ would probably detect and diagnose this disorder            

NEUROMODULATION

Massive global increase of brain plasticity is beneficial for a maturing brain and for the evolution of small worldliness. However, maturation is heavily depended on ‘Experience Dependent Plasticity thus experience control should be added via real-time experiences (including psychotherapy) or artificially controlled Virtual Reality experiences.     

Personality Disorders

Maturation and development of the Default-Mode-Network is a life-long process of interacting with the environmental  experiences. It is an experience –dependent plasticity process. Any disturbance to this process, including unstable environments, hampers Default-Mode-Network maturation. Immature mismatching biased internal  Representations cause non-adaptive faulty psychosocial functionality (personality disorders), deoptimization(mood alterations) and instability (anxiety) and possible fragmentation with psychotic vulnerability

IMAGING

Changes are expected in timescales of years. Most notably the network maturation should be measured in terms of small- worldliness  as it is expected that the maturing brain assumes small-world organization as it matures. Alife-trajectory of mature brains should be compared with trajectories of immature personality-disordered brains and a ‘bias measure’ would probably detect and diagnose this disorder  

NEUROMODULATION

Massive global increase of brain plasticity is beneficial for a maturing brain and for the evolution of small worldliness. However, maturation is heavily depended on ‘Experience Dependent Plasticity thus experience control should be added via real-time experiences (including psychotherapy) or artificially controlled Virtual Reality experiences.

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