Over-connected network inevitably demonstrates reduced plasticity thus contributes to De-optimization dynamics with growing mismatch (i.e., increase of Free Energy) between the Executive Network and Default Mode Network. The Executive Network representing instant occurrences and the Default Mode Network representing internal representations.
Imaging will involve increased correlation matrix entries, and connectivity graphs will show Small-World Network with increased clustering coefficients.The Executive Network and Default Mode Network should be assessed over-time, and a free-energy delta distance (Humming distance like measure) is expected to increase.Treatment will have to disconnect the overly connected network and increase plasticity.
Traditionally Serotonin Specific Reuptake Inhibitors (SSRI’s) are administrated also theoretically consider alternative (enhancing) neuronal-plasticity induction using cortical transcranial Magnetic Stimulation (TMS) transcranial Direct Current Stimulation tDCS, transcranial random Direct Current Stimulation trDCS. Additionally, consider Cognitive Behavioural Therapy like (CBT-like) personalized Virtual-Reality (VR) interventions. Use any intervention that will increase plasticity and reduce free energy. For Alogia consider modulating global integration using Dorsolateral Prefrontal Hub-related transcranial Alternating Current Stimulation (tACS) to disconnect global network (reduce Gamma synchronization).