Hyper-optimization dynamics with hyper matching  (i.e., reduced Free Energy) between the Executive Network and Default Mode Network. The Executive Network representing instant environmental occurrences  and the Default Mode Network representing internal representations. Thus optimization is the process of matching dynamics between internal representations and actual occurrences, with an emergent mood elevation effect..   
Imaging graphs of the Executive Network and Default Mode Network should be assessed over-time, and a free-energy delta distance (Humming distance like measure) evaluated. Blocking decrease of this measure will require increased network ‘rigidity’ by increasing connectivity dynamics which probably happens with antipsychotics.
Traditionally antipsychotics are administered Consider adding Virtual Reality (VR)  calming meditative environments