Immature rudimental biased Default Mode Network with internal configurations that are non-adaptive and biased in respect to occurring conditions generates Connectom spread instability with increased frustration on constraints that influence plasticity dynamics in away that may reduce free energy dynamics thus generating elevated (Manic) mood(emergent property) In addition general instability spread in the network generates anxious mood. Thus both anxious and manic mood emerge from such global network disturbance
Lifelong asessmnets of Default Mode Network graphs should be collected to identify small-world network disturbances and biases. Network instability of constraint frustration is expected. Additionally expect hyper-optimization decreased mismatch between the Default Mode network and the central executive network. Experience-dependent plasticity interventions together with increased connectivity to stabilize constraints is warranted.
For mania Traditionally antipsychotics are administered. Consider adding Virtual Reality (VR) calming meditative environments. For the Anxiety component consider adding Virtual Reality (VR) calming meditative experience-plasticity-inducing environments. When mania subsides and anxiety is controlled then treatment for personality disorder treatment traditionally involves psychotherapy (which is actually Experience-dependent-plasticity induction). Additionally, consider personalized Virtual-Reality (VR) psychotherapy. Use any intervention that will enhance Small World Network maturation.