Top-Down Hierarchical bias where higher level ideation biases incoming actual experience, by a faulty error-correction hierarchal dynamics. Normally bottom-up processes from lower-level brain networks is balanced by top-down controlling higher-level representations. The process is a dynamic error-prediction and correction process. In this disturbance the top-down process overrides the bottom-up evidence from the environment causing biased false ideations and delusions        
dorsolateral prefrontal cortical (dlPFC) connections to peripheral unimodal cortical regions are stronger then incoming signal from periphery this will show up on correlation matrixes and graph analysis. Treatment is aimed at dlPFC hubs via interneuronal dlPFC modulating activity
Traditionally antipsychotics are administrated theoretically also consider modulating cortical hierarchical balance using transcranial Alternating Current Stimulation (tACS) to desynchronize unimodal and transmodal cortices to reduce top-down biased effects (e.g., reduce Gamma synchronization between parietal and prefrontal cortices).  Consider administering opposing Delusions-related specific Virtual-Reality environments.